Secondary-active multidrug transporters can confer resistance on cells to pharmaceuticals by mediating their extrusion away from intracellular targets via substrate/H(+)(Na(+)) antiport.While the interactions of catalytic carboxylates in these transporters with coupling ions and substrates (drugs) have been studied in some detail, the functional im

Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) constitutes a source of great concern to health authorities worldwide.Herbal medicinal products are used as a significant treatment option for highly active antiretroviral therapies, the efficacies of Washer which are negatively impacted by the emergence of multidrug-resista

INTRODUCTION: The aim of this study is to investigate the demographic characteristics, mortality reasons and the factors that affect the mortality of the patients in general intensive care units.METHODS: In this study, 510 patients who were followed-up in our Intensive Care Units for one year and died were grouped according to age groups as AgeX

Glioblastoma multiforme (GBM) is rail cover the most malignant brain tumor in adults and it remains incurable.These tumors are very heterogeneous, resistant to cytotoxic therapies, and they show high rates of invasiveness.Therefore, patients face poor prognosis, and the survival rates remain very low.Previous research states that GBM contains a cel

Great ape populations are undergoing a dramatic decline, which is predicted to result in their extinction in Oven Door Hinge the wild from entire regions in the near future.Recent findings have particularly focused on African apes, and have implicated multiple factors contributing to this decline, such as deforestation, hunting, and disease.Less we